Central Missouri Vacations from $492

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Your Central Missouri Vacation

Whether you plan to visit Central Missouri for its rural countryside, spectacular views or something else entirely, this is one destination you'll never forget. Create your ultimate getaway with one of our Central Missouri vacation packages. With so much to see on a trip to Central Missouri, it can be tricky to know where to start. Kick off your journey in Columbia at Mizzou Arena and Columbia Mall — two much-loved attractions here. Another top city worth adding to your itinerary is Osage Beach. Don't miss Bagnell Dam and Lake of the Ozarks and Bagnell Dam Viewpoint. Find some travel buddies and start packing, because your Central Missouri vacation is only a few clicks away with Expedia.

The Latest Central Missouri vacation packages

Price found within the past 48 hours. Click for updated prices.
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
Coconuts RV Resort
Loganberry Inn
Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO
Capital O Amerihost Inn and Suites Fulton Hwy 54 MO
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Where to stay in Central Missouri

Find the best Central Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Central Missouri

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Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr., Lake Ozark, MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $132 total per night from Sep 7 to Sep 8
$132 total
Sep 7 - Sep 8
Total includes taxes and fees
7/10 Good! (1,004 reviews)
"Liked that it had several pools and was on the lake. Nice stay."

Reviewed on Aug 13, 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy, Osage Beach, MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $111 total per night from Aug 25 to Aug 26
$111 total
Aug 25 - Aug 26
Total includes taxes and fees
7.2/10 Good! (196 reviews)
"Two thumbs up"

Reviewed on Aug 1, 2025

Inn at Grand Glaize
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
Fully refundableReserve now, pay when you stay
$173 nightly
The price is $185 total per night from Sep 17 to Sep 18
$185 total
Sep 17 - Sep 18
Total includes taxes and fees
8.2/10 Very Good! (1,004 reviews)
"We enjoyed our stay but the property is just getting dated and worn for the price point. The rooms and facilities could use a facelift."

Reviewed on Aug 17, 2025

Margaritaville Lake Resort Lake of the Ozarks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.