Central Missouri Vacations from $272

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Your Central Missouri Vacation

Whether you plan to visit Central Missouri for its rural countryside, spectacular views or something else entirely, this is one destination you'll never forget. Create your ultimate getaway with one of our Central Missouri vacation packages. With so much to see on a trip to Central Missouri, it can be tricky to know where to start. Kick off your journey in Columbia at Mizzou Arena and Columbia Mall — two much-loved attractions here. Another top city worth adding to your itinerary is Osage Beach. Don't miss Bagnell Dam and Lake of the Ozarks and Bagnell Dam Viewpoint. Find some travel buddies and start packing, because your Central Missouri vacation is only a few clicks away with Expedia.

The Latest Central Missouri vacation packages

Price found within the past 48 hours. Click for updated prices.
Super 8 by Wyndham Lake of the Ozarks
Coconuts RV Resort
The Lake House Inn
Capital O Amerihost Inn and Suites Fulton Hwy 54 MO
Lakeside Oasis Room for 12!
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Where to stay in Central Missouri

Find the best Central Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Central Missouri

Discover the most popular places to visit in Central Missouri

What to do in Central Missouri

Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr., Lake Ozark, MO
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $132 total per night from Sep 7 to Sep 8
$132 total
Sep 7 - Sep 8
Total includes taxes and fees
7/10 Good! (1,008 reviews)
"Robert was amazing!"

Reviewed on Aug 9, 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa
Inn at Grand Glaize

Inn at Grand Glaize

2 out of 5
5142 Osage Beach Pkwy, Osage Beach, MO
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $108 total per night from Aug 17 to Aug 18
$108 total
Aug 17 - Aug 18
Total includes taxes and fees
7.2/10 Good! (192 reviews)
"Two thumbs up"

Reviewed on Aug 1, 2025

Inn at Grand Glaize
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Aug 24 to Aug 25
$69 total
Aug 24 - Aug 25
Total includes taxes and fees
8/10 Very Good! (412 reviews)
"The room and bathroom were tidy and easy to access. We has a good stay and could recommend the Baymont by Wyndham Columbia, MO."

Reviewed on Aug 10, 2025

Baymont by Wyndham Columbia, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.